Located along the course of the Natisone River, near to the Slovenian border, Pulfero boasts a landscape of remarkable interest and beauty. The road leading to the Pulfero pass became an important route since prehistoric times, allowing direct connection between the Friuli region and the Carnic-Carinthian region. During the Roman period, this connection was structured in the Via Appia which, starting from Aquileia, touched Cormons, San Pietro, Pulfero, Plezzo, Tarvisio, and ended in Virunum (near Klagenfurt). Many military expeditions passed through the pass (from Roman legions headed to Noricum and Pannonia to Napoleon), and almost all the invaders of Friuli entered (from the Lombards to the battle of Kobarid). The intensification of traffic brought the Natisone valleys to an evolved socio-economic phase, giving rise to new civil institutions, such as the Banca di Antro, an elective council in charge of the political-judicial affairs of the territory. This function diminished when the Venetians, having dismantled the patriarchy, blocked the Pulfero pass to favor the commerce of Gemona over that of Cividale. Notable works in the municipality include the church of San Giovanni in Antro and the picturesque church of San Giacomo Apostolo in Biacis.
